Are Male Reproductive Disorders a Common Entity
作者： K. A. BOISEN , K. M. MAIN , E. RAJPERT-DE MEYTS , N. E. SKAKKEBAEK
DOI: 10.1111/J.1749-6632.2001.TB03990.X
关键词:
摘要: : Growing evidence from clinical and epidemiological studies points to a synchronized increase in the incidence of male reproductive problems, such as genital abnormalities, testicular cancer, reduced semen quality, subfertility. Together these problems may reflect existence one common entity, dysgenesis syndrome (TDS). Experimental suggest that TDS is result disruption embryonal programming gonadal development during fetal life. The recent rise prevalence be causally linked endocrine disrupters affecting genetically susceptible individuals. We recommend future on trends reproduction do not focus symptom only, but take all aspects into account. potential impact adverse environmental factors role genetic polymorphisms involved requires further research.
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