Number of positive systematic sextant biopsies predicts surgical margin status at radical prostatectomy.

作者: Vida S Tigrani , Vivek Bhargava , Katsuto Shinohara , Joseph C Presti

DOI: 10.1016/S0090-4295(99)00211-3

关键词:

摘要: Abstract Objectives. To determine whether the number of positive sextant biopsies contributes to prediction surgical margins, as value systematic prostate in predicting margin status at radical prostatectomy is unclear. Methods. Consecutive patients (n = 108) who underwent retropubic and were retrospectively evaluated. Serum prostate-specific antigen, digital rectal examination, primary Gleason grade, score, location recorded for each patient. Radical specimens evaluated by step-section techniques 3 5-mm intervals. Univariate comparisons these variables was performed between negative groups using Mann-Whitney U test or chi-square analysis. Logistic regression analysis variables. Results. Twenty-two (20.4%) 108 had a because extension tumor through capsule. Patients with three more higher risk having (P 0.009). bilaterally either base midprostate likely have margin. The not significantly determined antigen. Multivariate logistic models created that consistently demonstrate best predictor status. Conclusions. This study demonstrated prostatectomy.

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