Thermoresponsiveness of posterior hypothalamic (PH) neurons of rats to scrotal and abdominal thermal stimulation.

摘要: The thermoresponsiveness of posterior hypothalamic (PH) neurons to localized, incremental thermal heating and cooling between 10-40 degrees C the abdomen or scrotum was determined in urethane anesthetized, male Sprague-Dawley rats whose core temperature maintained at 37 during testing. PH extracellular neuronal activity recorded along with changes gastrocnemius muscle EMG (Tms, indicative shivering thermogenesis) intrascapular brown adipose tissue (TIBATs, non-shivering thermogenesis). Seventy-five were following both scrotal abdominal trials stimulation. Nine percent classified as warm responsive (WRNs), 20% cold (CRNs), 71% nonresponsive (TNRNs), based on their coefficients (TCs). Mean TC for significantly increased warming 30-40 from mean same WRNs warming. Similarly, coefficient (i.e., more negative) (20-10 C) opposed CRNs cooling. No thermogenesis (no change muscle) significant increase IBAT temperatures) occurred these 21 acclimatized rats. results indicate that a small population are thermoresponsive localized physiological greater shown vs.