Liver function during mechanical circulatory support: from witness to prognostic determinant

摘要: In recent years, the treatment options for patients with severe cardiorespiratory failure have been extended by implementation of mechanical circulatory support (MCS). Identification that benefit most from this cost-intensive modality is central importance, but also challenging. Previous studies unravelled certain patient characteristics should be taken into account, such as age, weight, and underlying pathology, delay until MCS well tissue hypoxia prognostic factors. Relevant comorbidities included neurologic, renal, hepatic disorders. Of note, baseline liver function tests predicted outcome in on extracorporeal life (ECLS), including short-term long-term mortality. Most strikingly, increased levels alkaline phosphatase total bilirubin indicated unfavourable survival even after adjustment gender, left ventricular function, relevant known impaired renal diabetes. Therefore, assessment may regarded another piece complex puzzle our efforts perceiving ideal ECLS candidate positive outcome.