The role of dorsolateral prefrontal cortex in inhibition mechanism: A study on cognitive reflection test and similar tasks through neuromodulation

摘要: The main characteristic of the cognitive reflection test (CRT) is that it requires people to overcome a conflict. Solving this conflict (1) inhibitory control prepotent but incorrect responses and (2) mental set-shifting in order reframe problem reach meaningful solution. Based on well-known involvement dorsolateral prefrontal cortex (DLPFC) we hypothesised transcranial direct current stimulation (tDCS) DLPFC would modulate its contribution problem-solving performance. Thirty-nine participants undergoing anodal, cathodal, or sham tDCS were asked solve CRT similar mathematical problems structured induce an automatic, impulsive response. To provide multi-dimensional picture processes underlying responding assessed impulsivity traits using self-report measures recorded physiological indices biofeedback equipment. results indicated more likely after cathodal stimulation, i.e. when associated was reduced. Baseline values blood volume pulses predicted solution recognition, highlighting potential role individual differences solving. In conclusion, study provides evidence supporting modulation involved solving CRTs problems, thanks association mechanisms suppressing responses.