Targeting ion channels for cancer therapy by repurposing the approved drugs
作者： Vijay Pralhad Kale , Shantu G. Amin , Manoj K. Pandey
DOI: 10.1016/J.BBAMEM.2015.03.034
关键词:
摘要: Ion channels have been shown to be involved in oncogenesis and efforts are being poured target the ion channels. There many clinically approved drugs with as "off" targets. The question is, can these repurposed inhibit for cancer treatment? Repurposing of will not only save investors' money but also result safer patients. Advanced bioinformatics techniques availability a plethora open access data on FDA various indications omics large number types give ray hope look possibility repurposing those treatment. This article is part Special Issue entitled: Membrane transporters cancers.
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