Language processing in the occipital cortex of congenitally blind adults

作者: M. Bedny , A. Pascual-Leone , D. Dodell-Feder , E. Fedorenko , R. Saxe

DOI: 10.1073/PNAS.1014818108

关键词:

摘要: Humans are thought to have evolved brain regions in the left frontal and temporal cortex that uniquely capable of language processing. However, congenitally blind individuals also activate visual some verbal tasks. We provide evidence this activity fact reflects find individuals, behaves similarly classic regions: (i) BOLD signal is higher during sentence comprehension than linguistically degraded control conditions more difficult; (ii) modulated by phonological information, lexical semantic sentence-level combinatorial structure; (iii) functional connectivity with prefrontal thalamus increased relative sighted individuals. conclude for vision can take on processing as a result early experience. Innate microcircuit properties not necessary region become involved

参考文章(62)
Francisco Aboitiz, Ricardo García, The anatomy of language revisited. Biological Research. ,vol. 30, pp. 171- 183 ,(1997)
Youichi Saitoh, Atsushi Asahina, Kenji Tojo, Transcranial magnetic stimulation system ,(2012)
H. Burton, Visual cortex activity in early and late blind people. The Journal of Neuroscience. ,vol. 23, pp. 4005- 4011 ,(2003) , 10.1523/JNEUROSCI.23-10-04005.2003
Brigitte Röder, Wolfgang Teder-Sälejärvi, Anette Sterr, Frank Rösler, Steven A. Hillyard, Helen J. Neville, Improved auditory spatial tuning in blind humans Nature. ,vol. 400, pp. 162- 166 ,(1999) , 10.1038/22106
Leonardo G. Cohen, Pablo Celnik, Alvaro Pascual-Leone, Brian Corwell, Lala Faiz, James Dambrosia, Manabu Honda, Norihiro Sadato, Christian Gerloff, M. Dolores Catala´, Mark Hallett, Functional relevance of cross-modal plasticity in blind humans Nature. ,vol. 389, pp. 180- 183 ,(1997) , 10.1038/38278
Jack Fletcher, Sarah H. Broman, The changing nervous system : neurobehavioral consequences of early brain disorders Oxford University Press. ,(1999)
ADOLF Grünbaum, M Wartofsky, None, Boston Studies in the Philosophy of Science The British Journal for the Philosophy of Science. ,vol. 24, ,(1969) , 10.1007/978-94-010-3381-7
S Goldin-Meadow, H Feldman, The development of language-like communication without a language model Science. ,vol. 197, pp. 401- 403 ,(1977) , 10.1126/SCIENCE.877567
Barbara Landau, Lila R. Gleitman, Language and Experience: Evidence from the Blind Child ,(1988)