Semantic dementia combined with motor neuron disease.

摘要: Up to 20% of patients with behavioural variants frontotemporal dementia (FTD) also have motor neuron disease (MND); conversely, this comorbidity is rare in language FTD. A few been reported semantic (SD) combined MND. However, these demonstrated the clinical features MND advanced stage. We report a patient SD who symptoms an earlier stage disease. 61-year-old man visited our memory disorder clinic as result disturbance and dysarthria 8 months duration facial recognition impairment 3 duration. Neuropsychological tests revealed anomic aphasia, prosopagnosia, decreased fluency. brain MRI significant atrophies localized both anterior temporal lobes greater prominence on right side. Clinical examination electrophysiological studies confirmed diagnosis 17 after onset