Top notch targeting strategies in cancer: a detailed overview of recent insights and current perspectives.

Jennifer M. Bailey, Pankaj K. Singh, Michael A. Hollingsworth, Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins. Journal of Cellular Biochemistry. ,vol. 102, pp. 829- 839 ,(2007) , 10.1002/JCB.21509

Yanan Peng, Zongwei Li, Peng Yang, Ian P. Newton, Hua Ren, Lichao Zhang, Haili Wu, Zhuoyu Li, Direct contacts with colon cancer cells regulate the differentiation of bone marrow mesenchymal stem cells into tumor associated fibroblasts Biochemical and Biophysical Research Communications. ,vol. 451, pp. 68- 73 ,(2014) , 10.1016/J.BBRC.2014.07.074

Susana Ben-Neriah, King Tan, Ryan D. Morin, Stephen Opat, Laurie H. Sehn, Joseph M. Connors, Marco A. Marra, Andrew P. Weng, Christian Steidl, Randy D. Gascoyne, Robert Kridel, Barbara Meissner, Sanja Rogic, Merrill Boyle, Adele Telenius, Bruce Woolcock, Jay Gunawardana, Christopher Jenkins, Chris Cochrane, Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma Blood. ,vol. 119, pp. 1963- 1971 ,(2011) , 10.1182/BLOOD-2011-11-391474

Mirjam C. Boelens, Tony J. Wu, Barzin Y. Nabet, Bihui Xu, Yu Qiu, Taewon Yoon, Diana J. Azzam, Christina Twyman-Saint Victor, Brianne Z. Wiemann, Hemant Ishwaran, Petra J. ter Brugge, Jos Jonkers, Joyce Slingerland, Andy J. Minn, Exosome Transfer from Stromal to Breast Cancer Cells Regulates Therapy Resistance Pathways Cell. ,vol. 159, pp. 499- 513 ,(2014) , 10.1016/J.CELL.2014.09.051

Chulan Kwon, Paul Cheng, Isabelle N. King, Peter Andersen, Lincoln Shenje, Vishal Nigam, Deepak Srivastava, Notch post-translationally regulates β-catenin protein in stem and progenitor cells Nature Cell Biology. ,vol. 13, pp. 1244- 1251 ,(2011) , 10.1038/NCB2313

Xing Fan, Leila Khaki, Thant S. Zhu, Mary E. Soules, Caroline E. Talsma, Naheed Gul, Cheryl Koh, Jiangyang Zhang, Yue-Ming Li, Jarek Maciaczyk, Guido Nikkhah, Francesco DiMeco, Sara Piccirillo, Angelo L. Vescovi, Charles G. Eberhart, NOTCH Pathway Blockade Depletes CD133‐Positive Glioblastoma Cells and Inhibits Growth of Tumor Neurospheres and Xenografts Stem Cells. ,vol. 28, pp. 5- 16 ,(2009) , 10.1002/STEM.254

Yongzhao Shao, Farbod Darvishian, John F. Boylan, Iman Osman, Eva Hernando, Chanh Huynh, Laura Poliseno, Miguel F. Segura, Ratna Medicherla, Adele Haimovic, Silvia Menendez, Shulian Shang, Anna Pavlick, Correction: The Novel Gamma Secretase Inhibitor RO4929097 Reduces the Tumor Initiating Potential of Melanoma. PLOS ONE. ,vol. 6, ,(2011) , 10.1371/ANNOTATION/A89C089F-AE9D-4453-A314-37EFD5EFB126

Evanthia T. Roussos, Zuzana Keckesova, John D. Haley, David M. Epstein, Robert A. Weinberg, John S. Condeelis, AACR Special Conference on Epithelial-Mesenchymal Transition and Cancer Progression and Treatment Cancer Research. ,vol. 70, pp. 7360- 7364 ,(2010) , 10.1158/0008-5472.CAN-10-1208

Brendan C Dickson, Anna Marie Mulligan, Hui Zhang, Gina Lockwood, Frances P O'Malley, Sean E Egan, Michael Reedijk, High-level JAG1 mRNA and protein predict poor outcome in breast cancer Modern Pathology. ,vol. 20, pp. 685- 693 ,(2007) , 10.1038/MODPATHOL.3800785

Wan-Ching Yen, Marcus M Fischer, Fumiko Axelrod, Christopher Bond, Jennifer Cain, Belinda Cancilla, William R Henner, Rene Meisner, Aaron Sato, Jalpa Shah, Tracy Tang, Breanna Wallace, Min Wang, Chun Zhang, Ann M Kapoun, John Lewicki, Austin Gurney, Timothy Hoey, None, Targeting Notch Signaling with a Notch2/Notch3 Antagonist (Tarextumab) Inhibits Tumor Growth and Decreases Tumor-Initiating Cell Frequency Clinical Cancer Research. ,vol. 21, pp. 2084- 2095 ,(2015) , 10.1158/1078-0432.CCR-14-2808