Live Donor Adult Liver Transplantation Using Right Lobe Grafts

作者: Elizabeth A. Pomfret

DOI: 10.1001/ARCHSURG.136.4.425

关键词:

摘要: Hypothesis Live donor adult liver transplantation (LDALT) is a safe and efficacious treatment for patients with end-stage disease. Design Case-control study. Setting Hepatobiliary surgery unit. Patients From December 10, 1998, through April 2000, single team performed 15 LDALT procedures 2 simultaneous living kidney transplants. During this period, 66 potential donors were screened evaluated. Interventions Potential evaluated 3-dimensional helical computed tomographic scan, including volume renderings hepatic lobar volume, vascular anatomy, virtual resection planes, morphologic features. Suitable undergo complete medical psychiatric evaluation preoperative arteriography. Main Outcome Measures Donor demographics, data, operative hospital length of stay, morbidity. Results A total 38 men (58%) 28 women (42%) participating in LDALT. Two additional provided grafts at the time Thirty-two (48%) rejected either or recipient reasons, 10 (15%) elected not to participate after initial screening. Three-dimensional by scan predicted right lobe within 92% actual graft volume. morbidity, all complications, was 67% no mortality. Residual regenerated approximately 70% 1 week 80% month surgery. Conclusions an important component Significant morbidity encountered even careful selection. To minimize groups considering initiating programs should have expertise vena cava preservation using "piggyback" technique during transplantation.

参考文章(28)
CHRISTOPH E. BROELSCH, PETER F. WHITINGTON, JEAN C. EMOND, THOMAS G. HEFFRON, J. RICHARD THISTLETHWAITE, LARRY STEVENS, JAMES PIPER, SUSAN H. WHITINGTON, J. LANCE LICHTOR, Liver transplantation in children from living related donors. Surgical techniques and results. Annals of Surgery. ,vol. 214, pp. 428- 439 ,(1991) , 10.1097/00000658-199110000-00007
Jan Lerut, Raymond Reding, Jean-Bernard Otte, Etienne Sokal, J de Ville de Goyet, K Paul, Jean-Yves Hayez, M. Janssen, Dominique Latinne, F. Libert, R Rosati, Experience with living related liver transplantation in 63 children. Acta Gastro-enterologica Belgica. ,vol. 62, pp. 355- 362 ,(1999)
Amadeo Marcos, Robert A. Fisher, John M. Ham, Mitchell L. Shiffman, Arun J. Sanyal, Velimir A. C. Luketic, Richard K. Sterling, Ann S. Fulcher, Marc P. Posner, LIVER REGENERATION AND FUNCTION IN DONOR AND RECIPIENT AFTER RIGHT LOBE ADULT TO ADULT LIVING DONOR LIVER TRANSPLANTATION Transplantation. ,vol. 69, pp. 1375- 1379 ,(2000) , 10.1097/00007890-200004150-00028
Seiji Kawasaki, Masatoshi Makuuchi, Hidetoshi Matsunami, Yasuhiko Hashikura, Toshihiko Ikegami, Yuichi Nakazawa, Hisanao Chisuwa, Masaru Terada, Shin-ichi Miyagawa, Living Related Liver Transplantation in Adults Annals of Surgery. ,vol. 227, pp. 269- 274 ,(1998) , 10.1097/00000658-199802000-00017
Peter A. Singer, Mark Siegler, Peter F. Whitington, John D. Lantos, Jean C. Emond, J. Richard Thistlethwaite, Christoph E. Broelsch, Ethics of liver transplantation with living donors. The New England Journal of Medicine. ,vol. 321, pp. 620- 622 ,(1989) , 10.1056/NEJM198908313210919
T Tojimbara, S Fuchinoue, I Nakajima, S Sato, M Nakamura, H Ishida, I Koyama, K Utsumi, A Sannomiya, K Kitajima, M Kimikawa, T Tsugita, K Tanaka, K Takasaki, T Agishi, Analysis of the risk and surgical stress for donors in living-related liver transplantation. World Congress of the Transplantation Society. ,vol. 31, pp. 507- 508 ,(1999) , 10.1016/S0041-1345(98)01730-8
Silvano Raia, JoséRoberto Nery, Sérgio Mies, Liver transplantation from live donors. The Lancet. ,vol. 2, pp. 497- 497 ,(1989) , 10.1016/S0140-6736(89)92101-6
C. E. BROELSCH, J. C. EMOND, P. F. WHITINGTON, J. R. THISTLETHWAITE, A. L. BAKER, J. L. LICHTOR, Application of reduced-size liver transplants as split grafts, auxiliary orthotopic grafts, and living related segmental transplants. Annals of Surgery. ,vol. 212, pp. 368- 377 ,(1990) , 10.1097/00000658-199009000-00015
James J. Pomposelli, Sushil K. Gupta, Dimitrios C. Zacharoulis, Raul Landa, Arnold Miller, Rajesh Nanda, Surgical complication outcome (SCOUT) score: A new method to evaluate quality of care in vascular surgery Journal of Vascular Surgery. ,vol. 25, pp. 1007- 1015 ,(1997) , 10.1016/S0741-5214(97)70124-1