Formulation of medicines for children.

摘要: The development of age-adapted dosage forms and taste-masking bitter-tasting drugs administered orally for children, are formidable challenges formulation scientists. Childhood is a period maturation requiring knowledge developmental pharmacology to establish dose but the ability child manage different devices also changes. Paediatric formulations must allow accurate administration children widely varying age weight. Whilst oral route will be preferred long term use intravenous acutely ill, many designed adults, such as oro-dispersible tablets, buccal gels transdermal patches, would benefit if they contained an appropriate paediatric dose. at which can swallow conventional tablets great importance their safety. Liquid medicines usually recommended infants younger dhildren so mask unpleasant taste with sweeteners flavours crucial. More sophisticated granules may required there limitations on choice concentration excipients. There gaps in our about industry suitable preparations available all ranges. A CHMP points consider document soon released. research clinical feedback important because poor acceptability affect compliance, prescribing practice ultimately commercial viability.