Prospective surveillance of nosocomial device-associated bacteremia in three adult intensive units in Malaysia.

摘要: Nosocomial blood stream infection (or nosocomial bacteremia) is a common problem in hospitals worldwide, including Malaysia. A three-year prospective cohort study (October 2003-March 2007) of the incidences, risk factors, and patterns microorganisms causing bacteremia was conducted using validated surveillance form three intensive care units (ICUs) Center for Disease Control criteria were used to diagnose bacteremia. Patients monitored from admission until end point study, which first detection each patient. The frequency occurrence with clinical symptoms 10.7% (n = 23). Bacteremia observed occur within mean length stay 10 days ICU. rate device-related 10.4% per device utilization 95.9%/1000 patient days. total number 2309 period 2211 bacteria detected extended-spectrum beta-lactamases (ESBLs) Klebsiella pneumoniae 6); Pseudomonas aeruginosa Acinetobacter species 5); Methicillin-resistant Staphylococcus aureus (MRSA)(n 3); (non- ESBL) 2). Multivariable analysis Cox Proportional Hazard Model showed that predictors developing cancer, MRSA carriage, duration central venous catheter (CVC) infusion, change CVC, administration hydrocortisone drugs. These results indicate combination nursing medical interventions as well patients' severity illness could lead Strategic implementation quality assurance measures ICUs help control this problem.