Urinary excretion of hyaluronan in man

作者: Ulla Lindqvist , U. B. Laurent , A. Engström-Laurent , K. Lilja , L. Brunnberg

DOI: 10.1080/00365518709168948

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摘要: A specific assay for hyaluronan (hyaluronic acid) has been applied to the determination of polysaccharide in urine. The excretion 22 healthy subjects was 330 micrograms/24 h (SD 77). correlated with body weight and therefore somewhat higher males than females. molecular main fraction urinary range 4000 12,000 accordance hypothesis that it originates from blood arises by glomerular filtration. small could have produced tract. Hyaluronan male female urine displayed same distributions. Patients rheumatoid arthritis primary biliary cirrhosis showed a two-fold three-fold increase, respectively, concurrently high levels serum. patient Werner's syndrome ten-fold increase both serum

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