Methods and compositions for nucleic acid analysis
作者： Serge Saxonov
DOI:
关键词:
摘要: Provided herein are methods, compositions, and kits for assays, many of which involve amplification reactions such as digital PCR or droplet PCR. The assays may be used applications sequencing, copy number variation analysis, others. In some cases, the subdividing a sample into multiple partitions (e.g., droplets) merging with other that comprise adaptors barcodes.
lens.org 参考文章(1,025)
Lucia Granieri, Droplet-based microfluidics and engineering of tissue plasminogen activator for biomedical applications Strasbourg. ,(2009)
Geeringaa Hansu, Biyutsuheraa Manfureeto, Kurinkujiiku Berunto, Kogurin Berunto, Method and apparatus for producing dispersion ,(1983)
Jan Trnovsky, Patricia McGrath, Gel microdroplets in genetic analysis ,(2003)
Tadao Nakajima, Masataka Shimizu, Production of emulsion ,(1988)
Jwa-Min Nam, So-Jung Park, Chad A. Mirkin, Bio-barcodes based on oligonucleotide-modified nanoparticles Journal of the American Chemical Society. ,vol. 124, pp. 3820- 3821 ,(2002) , 10.1021/JA0178766
Kazuo Matsuyama, 一雄 松山, Micro mixer and fluid mixing method using the same ,(2005)
Serge Saxonov, Michael Lucero, Kevin Dean Ness, Philip Belgrader, Billy Wayne Colston, Benjamin Joseph Hindson, Methods and compositions for detecting copy number and chromosome aneuploidy by ligation probes and partitioning the ligated products prior to amplification ,(2010)
Suzuki Takahiro, Kubota Yuji, Noritomi Hidetomi, Noritomi Yasuko, APPARATUS FOR PRODUCING FINE PARTICLE, EMULSIFIER HOLDING PART, METHOD FOR PRODUCING FINE PARTICLE AND METHOD FOR PRODUCING MOLECULAR FILM ,(2007)
Nabetani Hiroshi, Takao Hironoshin, Kikuchi Yuji, Sano Yoh, Nakajima Mitsutoshi, Kawakatsu Takahiro, Kobayashi Isao, Continuous manufacturing method for microspheres and apparatus therefor ,(2001)
Hu Yiqiao, Tang Xiaolei, Yuan Ahu, Ding Dawei, Wu Jinhui, Method for preparing protein nanoparticles for delivering pharmacological active substances inside human bodies ,(2013)