Exertional rhabdomyolysis: Does elevated blood creatine kinase foretell renal failure?

作者: Priscilla M. Clarkson , E. Randy Eichner

DOI: 10.1007/S11932-006-0030-3

关键词:

摘要: Recreational activity frequently produces large increases in circulating CK without consequence. Thus, high levels alone do not portend renal failure. Most cases of exertional rhabdomyolysis can, and probably do, resolve on their own treatment. When taking a blood sample during routine check, for example monitoring patients statin therapy, may indicate that strenuous exercise was performed the previous 10 days. Patients should be queried as to history this time. Snow shoveling, dirt lifting lowering heavy boxes, resistance training, excessive calisthenics (such push-ups pull-ups) are exercises dramatically increase several days due forceful eccentric contractions. In addition elevated CK, factors such underlying disease, dehydration, environmental heat stress, or genetic predisposition (eg, sickle cell trait) likely required result acute failure [8]. Persons who present emergency room with painful, swollen muscles about 2 after bout monitored kidney function (BUN creatinine), evidence myoglobinuria regarding hydration, stress exercise, possible trauma. rhabdomyolysis, especially laboratory situations, up 100,000 U/L absence nephrotoxic have been found consequence when no treatment is provided. However, because few data confirm clinical situation which there comorbidities, it remains conservative prudent hydrate intravenously monitor closely help avoid hyperkalemia and/or face fulminant rhabdomyolysis.

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