Essential genes as antimicrobial targets and cornerstones of synthetic biology.
作者： Mario Juhas , Leo Eberl , George M. Church
DOI: 10.1016/J.TIBTECH.2012.08.002
关键词:
摘要: Essential genes are absolutely required for the survival of any living entity. Investigation of essential genes is therefore expected to advance tremendously our understanding of the …
core.ac.uk
harvard.edu 
sci-hub.se 参考文章(77)
Byung Jo Yu, Sun Chang Kim, Minimization of the Escherichia coli genome using the Tn5-targeted Cre/loxP excision system. Methods of Molecular Biology. ,vol. 416, pp. 261- 277 ,(2008) , 10.1007/978-1-59745-321-9_17
Kishore R. Sakharkar, Meena K. Sakharkar, Vincent T. K. Chow, Biocomputational strategies for microbial drug target identification. Methods in molecular medicine. ,vol. 142, pp. 1- 9 ,(2008) , 10.1007/978-1-59745-246-5_1
Chun-Ting Zhang, Ren Zhang, Gene essentiality analysis based on DEG, a database of essential genes. Methods of Molecular Biology. ,vol. 416, pp. 391- 400 ,(2008) , 10.1007/978-1-59745-321-9_27
Harris H. Wang, George M. Church, Multiplexed genome engineering and genotyping methods applications for synthetic biology and metabolic engineering. Methods in Enzymology. ,vol. 498, pp. 409- 426 ,(2011) , 10.1016/B978-0-12-385120-8.00018-8
E. Pennisi, Replacement Genome Gives Microbe New Identity Science. ,vol. 316, pp. 1827- 1827 ,(2007) , 10.1126/SCIENCE.316.5833.1827A
Haojie Yu, Xin Yan, Weiliang Shen, Yujia Shen, Ji Zhang, Shunpeng Li, Efficient and Precise Construction of Markerless Manipulations in the Bacillus subtilis Genome Journal of Microbiology and Biotechnology. ,vol. 20, pp. 45- 53 ,(2010) , 10.4014/JMB.0904.04051
M. A. Fischbach, C. T. Walsh, Antibiotics For Emerging Pathogens Science. ,vol. 325, pp. 1089- 1093 ,(2009) , 10.1126/SCIENCE.1176667
Sanie Mnaimneh, Armaity P Davierwala, Jennifer Haynes, Jason Moffat, Wen-Tao Peng, Wen Zhang, Xueqi Yang, Jeff Pootoolal, Gordon Chua, Andres Lopez, Miles Trochesset, Darcy Morse, Nevan J Krogan, Shawna L Hiley, Zhijian Li, Quaid Morris, Jörg Grigull, Nicholas Mitsakakis, Christopher J Roberts, Jack F Greenblatt, Charles Boone, Chris A Kaiser, Brenda J Andrews, Timothy R Hughes, Exploration of essential gene functions via titratable promoter alleles Cell. ,vol. 118, pp. 31- 44 ,(2004) , 10.1016/J.CELL.2004.06.013
B. J. Akerley, E. J. Rubin, V. L. Novick, K. Amaya, N. Judson, J. J. Mekalanos, A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae Proceedings of the National Academy of Sciences of the United States of America. ,vol. 99, pp. 966- 971 ,(2002) , 10.1073/PNAS.012602299
Yota Tsuge, Nobuaki Suzuki, Masayuki Inui, Hideaki Yukawa, Random segment deletion based on IS31831 and Cre/loxP excision system in Corynebacterium glutamicum Applied Microbiology and Biotechnology. ,vol. 74, pp. 1333- 1341 ,(2007) , 10.1007/S00253-006-0788-5