Functionalized calcium phosphate artificial bone and joint compositions and methods of use and manufacture

摘要: A functionalized composition and resulting body or prosthesis for in vitro vivo use comprising at least one calcium phosphate containing phase that is with a linker group of an organic acid molecule, phosphonic acid, amine, Ν,Ν-dicyclohexylcarbodiimide, 3-maleimidopropionic N-hydroxysuccinimide ester, wherein the provides reactive location attachment chemical biologically active moiety to phase. The compositions have pliable physical property when mixed water adhere natural bone subsequently harden ambient temperatures. Methods manufacturing artificial may be used as bones, joints, in-vitro support structures, in-vivo structures cells, tissues, organs, nerve growth regeneration are disclosed. repairing bone, vertebrae, tissue using provided.