New β-carboline and indole alkaloids from Actinomycete Actinomadura sp. BCC 24717

作者: Jittra Kornsakulkarn , Siriporn Saepua , Tanapong Boonruangprapa , Sumalee Suphothina , Chawanee Thongpanchang

DOI: 10.1016/J.PHYTOL.2013.06.007

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摘要: Abstract Four new β -carbolines 1–4 and two indoles 5–6 were isolated together with thirteen known compounds from actinomycete, Actinomadura BCC 24717. Structures of the compounds, 1–6, determined by NMR spectroscopic MS spectrometric analyses. Compound 4 exhibited cytotoxicity to Vero cells compound 6 showed antifungal activity IC 50 35.91 μg/mL 41.97 μg/mL, respectively.

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