The β‐thalassaemia mutations in the population of Cyprus
作者： E. Baysal , K. Indrak , G. Bozkurt , A. Berkalp , E. Aritkan
DOI: 10.1111/J.1365-2141.1992.TB03000.X
关键词:
摘要: We have identified the beta-thalassaemia alleles in nearly all known Turkish Cypriot homozygotes and over 700 Greek heterozygotes living on island of Cyprus. The data confirmed earlier observations that IVS-I-100 (G-->A) mutation is present for about 74-80%, while three other [IVS-II-745 (C-->G), IVS-I-6 (T-->C), IVS-I-1 (G-->A)] occur at frequencies 5-8%. Nearly identical percentages were observed two groups, quite different from those patients Greece Turkey. This suggests close contacts between communities during many centuries without a major recent influence or carriers.
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