Neonatal and pediatric antimicrobial stewardship programs in Europe-defining the research agenda.

摘要: The relationship between suboptimal use of antimicrobials and antimicrobial resistance has become increasingly clear. Despite significant international effort aimed at reducing inappropriate prescribing in hospitals, remains a major public health threat. Antimicrobial Stewardship Programs (ASPs) comprise series measures optimizing the antimicrobials, while improving quality patient care promoting cost-effectiveness. This discussion article aims to summarize some approaches that have been used neonatal pediatric ASPs, with particular focus on European healthcare setting. Current evidence demonstrates ASPs be safe, practical implement, generally cost-effective possibly associated reduction rates. review identified that, despite recognized need for additional information implementation, published data derives mainly from United States, very few reports formal children's hospitals. Consequently, optimal method implementation unknown within Future research needs include novel study designs how best introduce monitoring clinically relevant outcomes cost-effectiveness improved measurement impact resistance.