Squamous cell carcinoma antigen, platelet distribution width, and prealbumin collectively as a marker of squamous cell cervical carcinoma

摘要: BACKGROUND Squamous cell cervical carcinoma is the most common gynecological malignant disorder worldwide. Early detection of squamous needed for proper clinical management. antigen (SCCA) commonly used as a tumor marker carcinoma. Platelet distribution width (PDW) an indicator platelet activation. Prealbumin negative acute-phase protein. OBJECTIVE The aim this study was to investigate ability SCCA, PDW, and prealbumin individually or in combination, distinguish between control subjects. MEHTODS Two hundred twenty patients with 211 subjects were included study. Patients' characteristics hematologic tests data at initial diagnosis collected. RESULTS Our results showed that SCCA PDW higher, lower than Single biomarker had AUC value ranging from 0.753 0.845 PDW. combination increased 0.900 (p< 0.0001). In addition, exhibited significantly larger 0.917 (0.887-0.942), higher those any single marker. CONCLUSIONS combined use can accurately This promising approach could be helpful early