Reducing Suicidal Ideation and Depression in Older Primary Care Patients: 24-Month Outcomes of the PROSPECT Study

作者: George S. Alexopoulos , Charles F. Reynolds , Martha L. Bruce , Ira R. Katz , Patrick J. Raue

DOI: 10.1176/APPI.AJP.2009.08121779

关键词:

摘要: Objective: The Prevention of Suicide in Primary Care Elderly: Collaborative Trial (PROSPECT) evaluated the impact a care management intervention on suicidal ideation and depression older primary patients. This is first report outcomes over 2-year period. Method: Study participants were patients 60 years age or (N=599) with major minor selected after screening 9,072 randomly identified 20 practices assigned to provide either PROSPECT usual care. consisted services 15 trained managers, who offered algorithm-based recommendations physicians helped treatment adherence 24 months. Results: Compared receiving care, those had higher likelihood antidepressants and/or psychotherapy (84.9%–89% versus 49%–62%) 2.2 times greater decline Treatment response occurre...

参考文章(29)
A. M. Kleinman, S. K. Goldsmith, W. E. Bunney, T. C. Pellmar, Reducing Suicide: A National Imperative ,(2013)
Marshal F. Folstein, Susan E. Folstein, Paul R. McHugh, “Mini-mental state” Journal of Psychiatric Research. ,vol. 12, pp. 189- 198 ,(1975) , 10.1016/0022-3956(75)90026-6
Joseph J. Gallo, Hillary R. Bogner, Knashawn H. Morales, Edward P. Post, Julia Y. Lin, Martha L. Bruce, The Effect of a Primary Care Practice–Based Depression Intervention on Mortality in Older Adults Annals of Internal Medicine. ,vol. 146, pp. 689- 698 ,(2007) , 10.7326/0003-4819-146-10-200705150-00002
T WITTE, T JOINERJR, G BROWN, A BECK, A BECKMAN, P DUBERSTEIN, Y CONWELL, Factors of suicide ideation and their relation to clinical and other indicators in older adults. Journal of Affective Disorders. ,vol. 94, pp. 165- 172 ,(2006) , 10.1016/J.JAD.2006.04.005
R Thomas, Ten Have, Allen R Kunselman, Erik P Pulkstenis, J Richard Landis, Mixed effects logistic regression models for longitudinal binary response data with informative drop-out. Biometrics. ,vol. 54, pp. 367- 383 ,(1998) , 10.2307/2534023
Jeffrey M. Lyness, Eric D. Caine, Deborah A. King, Christopher Cox, Ziggy Yoediono, Psychiatric disorders in older primary care patients Journal of General Internal Medicine. ,vol. 14, pp. 249- 254 ,(1999) , 10.1046/J.1525-1497.1999.00326.X
Wayne J Katon, Michael Schoenbaum, Ming-Yu Fan, Christopher M Callahan, John Williams, Enid Hunkeler, Linda Harpole, Xiao-Hua Andrew Zhou, Christopher Langston, Jürgen Unützer, IMPACT Investigators, Cost-effectiveness of improving primary care treatment of late-life depression. Archives of General Psychiatry. ,vol. 62, pp. 1313- 1320 ,(2005) , 10.1001/ARCHPSYC.62.12.1313
Benoit H. Mulsant, George S. Alexopoulos, Charles F. Reynolds, Ira R. Katz, Robert Abrams, David Oslin, Herbert C. Schulberg, , Pharmacological treatment of depression in older primary care patients: the PROSPECT algorithm. International Journal of Geriatric Psychiatry. ,vol. 16, pp. 585- 592 ,(2001) , 10.1002/GPS.465