Attention and Motivated Response to Simulated Male Advertisement Call Activates Forebrain Dopaminergic and Social Decision-Making Network Nuclei in Female Midshipman Fish.

摘要: Little is known regarding the coordination of audition with decision-making and subsequent motor responses that initiate social behavior including mate localization during courtship. Using midshipman fish model, we tested hypothesis time spent by females attending responding to advertisement call correlated activation a specific subset catecholaminergic (CA) network (SDM) nuclei underlying auditory- driven sexual motivation. In addition, quantified relationship neural between CA SDM in all responders goal providing map functional connectivity circuitry motivated state responsive acoustic cues localization. order make baseline qualitative comparison this brain unmotivated females, made similar correlative who were unresponsive playback. Our results support an important role for dopaminergic neurons periventricular posterior tuberculum ventral thalamus, putative A11 A13 tetrapod homologues, respectively, as well parvocellular preoptic area dorsomedial telencephalon, (laterobasal amygdala homologue) auditory attention appetitive fishes. These findings may also offer insights into function these highly conserved context auditory-driven reproductive across vertebrates.