The use of the bootstrap statistical method for the pharmacoeconomic cost analysis of skewed data.

摘要: In pharmacoeconomics, the comparison of costs 2 different drugs used for same treatment is great interest. The problem especially challenging when are likely to produce costly adverse effects in a small number patients, which often case. data then skewed and traditional statistical methods analyse difference mean produced by treatments may be inappropriate. bootstrap method presented as an alternative approach. A pharmacoeconomic cost-analysis example throughout this article.