ADME of Herbal Dietary Supplements
作者： Sheela PaiBir , Sadayappan V. Rahavendran
DOI: 10.1002/9780470921920.EDM039
关键词:
摘要: In spite of modern medical advances, herbal dietary supplements continue to be widely used for health maintenance, disease prevention, and even treatment. The ADME mechanisms the known herb–drug interactions involve, in most cases, inhibition or induction hepatic intestinal drug-metabolizing enzymes cytochrome P450 family, and/or drug transporters. This chapter provides a review potential based on literature reports those herbs that are popularly United States. Relevant clinical human vitro studies have evaluated metabolism-based absorption-based understand between these commonly drugs also reviewed. Keywords: herb–drug interactions; cytochrome P450; P-glycoprotein; US Food Drug Administration (FDA); commonly States
sci-hub.se 参考文章(244)
Herbal medicines and postoperative haemorrhage. Anaesthesia. ,vol. 60, pp. 725- 726 ,(2005) , 10.1111/J.1365-2044.2005.04276.X
M I Mohammed Abdul, X Jiang, K M Williams, R O Day, B D Roufogalis, W S Liauw, H Xu, A J McLachlan, Pharmacodynamic interaction of warfarin with cranberry but not with garlic in healthy subjects British Journal of Pharmacology. ,vol. 154, pp. 1691- 1700 ,(2009) , 10.1038/BJP.2008.210
Arabelle Pfrunder, Monika Schiesser, Simone Gerber, Manuel Haschke, Johannes Bitzer, Juergen Drewe, Interaction of St John's wort with low‐dose oral contraceptive therapy: a randomized controlled trial British Journal of Clinical Pharmacology. ,vol. 56, pp. 683- 690 ,(2003) , 10.1046/J.1365-2125.2003.02005.X
H Xu, K M Williams, W S Liauw, M Murray, R O Day, A J McLachlan, Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazide. British Journal of Pharmacology. ,vol. 153, pp. 1579- 1586 ,(2008) , 10.1038/SJ.BJP.0707685
B. Nageshwar Rao, Maddi Srinivas, Y. Shravan Kumar, Y. Madhusudan Rao, Effect of silymarin on the oral bioavailability of ranitidine in healthy human volunteers. Drug metabolism and drug interactions. ,vol. 22, pp. 175- 186 ,(2007) , 10.1515/DMDI.2007.22.2-3.175
B GURLEY, S GARDNER, M HUBBARD, D WILLIAMS, W GENTRY, J CARRIER, I KHAN, D EDWARDS, A SHAH, In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto Clinical Pharmacology & Therapeutics. ,vol. 76, pp. 428- 440 ,(2004) , 10.1016/J.CLPT.2004.07.007
Angelo A. Izzo, Edzard Ernst, Interactions between herbal medicines and prescribed drugs: an updated systematic review. Drugs. ,vol. 69, pp. 1777- 1798 ,(2009) , 10.2165/11317010-000000000-00000
J Engelsen, JD Nielsen, K Winther, None, Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thrombosis and Haemostasis. ,vol. 87, pp. 1075- 1076 ,(2002) , 10.1055/S-0037-1613135
Martha R Harkey, Gary L Henderson, M Eric Gershwin, Judith S Stern, Robert M Hackman, Variability in commercial ginseng products: an analysis of 25 preparations. The American Journal of Clinical Nutrition. ,vol. 73, pp. 1101- 1106 ,(2001) , 10.1093/AJCN/73.6.1101
Furong Qiu, Guangji Wang, Rong Zhang, Jianguo Sun, Jian Jiang, Yueming Ma, Effect of danshen extract on the activity of CYP3A4 in healthy volunteers British Journal of Clinical Pharmacology. ,vol. 69, pp. 656- 662 ,(2010) , 10.1111/J.1365-2125.2010.03624.X