Accumulation of long-chain acylcarnitine and 3-hydroxy acylcarnitine molecular species in diabetic myocardium: identification of alterations in mitochondrial fatty acid processing in diabetic myocardium by shotgun lipidomics.

作者: Xiong Su , Xianlin Han , David J. Mancuso , Dana R. Abendschein , Richard W. Gross

DOI: 10.1021/BI047773A

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摘要: Diabetic cardiomyopathy is the result of maladaptive changes in energy homeostasis. However, biochemical mechanisms underlying dysfunctional lipid metabolism diabetic myocardium are incomple...

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