Risk factors for nosocomial colonization with multiresistantAcinetobacter baumannii

摘要: A six-month prospective survey was carried out in a university hospital to assess the incidence ofAcinetobacter baumannii cross-contamination and identify risk factors for colonization. Clinical isolates obtained during study period were biotyped genotyped by pulsed-field gel electrophoresis after Apal macrorestriction of total DNA. Casecontrol univariate multivariate analyses performed forAcinetobacter One hundred forty-seven patients hospitalized 36 units colonized or infected, whom 52 three intensive care units. The urinary (29 %) bronchopulmonary tracts (26 most frequently sites. Nine major restriction patterns identified: two exhibited epidemic multiresistant strains biotype 9 which isolated from 65 ten Multivariate analysis showed that case-patients (a) more likely than noninfected controls be male, have been previously another unit had longer stays before colonization hyperalimentation; (b) with other gram-negative bacilli hospitalization, received treatment third-generation cephalosporins catheter. high withAcinetobacter can thus attributed frequent use broadspectrum antibiotics. Colonized appear source as spread throughout hospital.