Pharmaceutical Polymer Gels in Drug Delivery

摘要: Polymer gels are being developed at prolific pace as prominent delivery systems to circumvent obstacles in drug and impart easier application of therapeutics. A large number molecules migrate into an elastic cross-linked network long polymers inflated with a solvent such water, causing the swelling resulting formation aggregate known polymer gel. utilized different technologies, including delivery, biomedical devices, biosensors, tissue engineering, actuators, even cosmetics food. Recently, there has been growing interest smart constituting new generation biomaterials that respond significant changes due little environment. The form referred “smart” or “stimuli-sensitive” “environmentally” sensitive polymers, they can be classified on basis their structure (superporous gels, shape memory artificial protein gels) stimuli (pH-sensitive temperature-sensitive thermoresponsive analyte-sensitive gels). gel prepared by covalent non-covalent cross-linking (chemical thermally irreversible physical thermoreversible respectively), it evaluated for morphology, rheological behavior, adhesion, spreadability, vitro diffusion/permeation, vivo stability formulation. presence various biomarkers have extensively used targeting specific disease conditions. This chapter will organized four separate sections: defining concept gels; describing types, formulation, evaluation illustrating applications especially context delivery; recent advances future perspectives.