The use of a multiple injection insulin regimen for diabetic adolescents

摘要: The treatment of 20 adolescent diabetics (M:F 9:11, age range 10-18 years) was changed from twice daily injection short and intermediate acting insulin to a multiple regimen long zinc suspension (Ultratard, Novo Laboratories, Basingstoke, Hants) once daily, with soluble (Actrapid, Novo) preprandially two or three times using device (NovoPen, Novo). effiects on dose, diabetic control as assessed by glycosylated haemoglobin values growth were studied after one year. Total dosage unchanged but the flexibility welcomed no patients requested return fewer injections. Symptomatic improvement occurred especially in those who had frequent severe hypoglycaemic reactions regimen. Mean increased sharply at months slightly six months, then fell year mean value significantly lower than (p<0.0l). Growth rates showed significant change. The best results achieved remained acceptable when Ultratard given separate bedtime.