摘要: In the present thesis, observational effects of dust grain growth and sedimentation in circumstellar discs are investigated. The grains from some nanometres diameter as found inter- stellar medium towards planetesimal bodies meters is an important step formation planets. However, this process currently not entirely un- derstood. Especially, literature several ‘barriers’ discussed that apparently prohibit effective grains. Hence, it particular interest to compare theories data respect. State-of-the-art radiative transfer techniques allow one derive observable quantities theoretical models comparison. In generic tracers spatially high resolution multi-wavelength images identified for first time. Further, a possibility detect trapping mechanism by local pressure maxima using new interferometer, ALMA, established. By fitting parametric observations disc Bok globule CB 26, unexpected features system revealed, such large inner void interpret without need growth. same way, their interpretation IRAS 04302+2247 provide evidence time radial dependent settling images. Moreover, thesis applicability T Tauri paradigm high-mass candidate 18151-1208 demonstrated.