Prevalence of metabolic syndrome among urban Indian adolescents and its relation with insulin resistance (HOMA-IR).

摘要: Aim: To assess prevalence of metabolic syndrome (MS) in urban Indian adolescents. MS adolescents is a forerunner diabetes mellitus and cardiovascular disease adults, therefore, its identification provides an opportunity to intervene with lifestyle changes prevent progression into adulthood. We randomly selected 900 (300 for each group) participate the study from total 15,101 (10–18 years) who were grouped as normal, overweight, obese (total population). Methods: From adolescents, 695 consented underwent detailed anthropometric biochemical evaluation, these constituted population. was defined by criteria proposed International Diabetes Federation (MS-IDF) Adult Treatment Panel (MS-ATP). The population used calculate based on distribution different BMI categories this larger sample (n = 15,101). Results: Calculated 4.3% 3.0% using MS-ATP MS-IDF criteria, respectively. Among population, higher girls than boys (MS-ATP, G: 22.3% vs. B: 16.6%, p = 0.03; MS-IDF, 20.5% 13.5%, 0.006). most common component MS- ATP central obesity (89.8% 100.0%, p < 0.00001), followed hypertriglyceridemia (83.0% 82.2%, 0.35), low high density lipoproteincholesterol (71.1% 71.2%, 0.48), hypertension (44.4% 44.9%, 0.025), dysglycemia (40.0% 34.7%, 0.94). mean serum insulin levels HOMA-IR progressively increased increasing number components present individual. Conclusions: Metabolic overweight