Organization of the Drosophila larval visual circuit.

作者: Ivan Larderet , Pauline MJ Fritsch , Nanae Gendre , G Larisa Neagu-Maier , Richard D Fetter

DOI: 10.7554/ELIFE.28387

关键词:

摘要: Visual systems transduce, process and transmit light-dependent environmental cues. Computation of visual features depends on photoreceptor neuron types (PR) present, organization the eye wiring underlying neural circuit. Here, we describe circuit architecture system Drosophila larvae by mapping synaptic diagram neurotransmitters. By contacting different targets, two larval PR-subtypes create converging pathways potentially computation ambient light intensity temporal changes already within this first processing center. Locally processed information then signals via dedicated projection interneurons to higher brain areas including lateral horn mushroom body. The stratified structure optic neuropil (LON) suggests common organizational principles with adult fly vertebrate systems. complete LON paves way understanding how circuits reduced numerical complexity control wide ranges behaviors.

参考文章(104)
F. Javier Bernardo-Garcia, Cornelia Fritsch, Simon G. Sprecher, The transcription factor Glass links eye field specification with photoreceptor differentiation inDrosophila Development. ,vol. 143, pp. 1413- 1423 ,(2016) , 10.1242/DEV.128801
Tihana Jovanic, Casey Martin Schneider-Mizell, Mei Shao, Jean-Baptiste Masson, Gennady Denisov, Richard Doty Fetter, Brett Daren Mensh, James William Truman, Albert Cardona, Marta Zlatic, Competitive Disinhibition Mediates Behavioral Choice and Sequences in Drosophila. Cell. ,vol. 167, pp. 858- 870 ,(2016) , 10.1016/J.CELL.2016.09.009
Damon A. Clark, Jonathan B. Demb, Parallel Computations in Insect and Mammalian Visual Motion Processing. Current Biology. ,vol. 26, ,(2016) , 10.1016/J.CUB.2016.08.003
Ming Wu, Aljoscha Nern, W Ryan Williamson, Mai M Morimoto, Michael B Reiser, Gwyneth M Card, Gerald M Rubin, Visual projection neurons in the Drosophila lobula link feature detection to distinct behavioral programs. eLife. ,vol. 5, ,(2016) , 10.7554/ELIFE.21022
William F Tobin, Rachel I Wilson, Wei-Chung Allen Lee, Wiring variations that enable and constrain neural computation in a sensory microcircuit eLife. ,vol. 6, ,(2017) , 10.7554/ELIFE.24838
Lia Frenkel, Nara I. Muraro, Andrea N. Beltrán González, María S. Marcora, Guillermo Bernabó, Christiane Hermann-Luibl, Juan I. Romero, Charlotte Helfrich-Förster, Eduardo M. Castaño, Cristina Marino-Busjle, Daniel J. Calvo, M. Fernanda Ceriani, Organization of Circadian Behavior Relies on Glycinergic Transmission. Cell Reports. ,vol. 19, pp. 72- 85 ,(2017) , 10.1016/J.CELREP.2017.03.034
Tim-Henning Humberg, Simon G. Sprecher, Age- and wavelength-dependency of drosophila larval phototaxis and behavioral responses to natural lighting conditions Frontiers in Behavioral Neuroscience. ,vol. 11, pp. 66- 66 ,(2017) , 10.3389/FNBEH.2017.00066
Katharina Eichler, Feng Li, Ashok Litwin-Kumar, Youngser Park, Ingrid Andrade, Casey M. Schneider-Mizell, Timo Saumweber, Annina Huser, Claire Eschbach, Bertram Gerber, Richard D. Fetter, James W. Truman, Carey E. Priebe, L. F. Abbott, Andreas S. Thum, Marta Zlatic, Albert Cardona, The complete connectome of a learning and memory centre in an insect brain Nature. ,vol. 548, pp. 175- 182 ,(2017) , 10.1038/NATURE23455
Matthew E Berck, Avinash Khandelwal, Lindsey Claus, Luis Hernandez-Nunez, Guangwei Si, Christopher J Tabone, Feng Li, James W Truman, Rick D Fetter, Matthieu Louis, Aravinthan DT Samuel, Albert Cardona, The wiring diagram of a glomerular olfactory system eLife. ,vol. 5, ,(2016) , 10.7554/ELIFE.14859
Philipp Schlegel, Michael J Texada, Anton Miroschnikow, Andreas Schoofs, Sebastian Hückesfeld, Marc Peters, Casey M Schneider-Mizell, Haluk Lacin, Feng Li, Richard D Fetter, James W Truman, Albert Cardona, Michael J Pankratz, Synaptic transmission parallels neuromodulation in a central food-intake circuit eLife. ,vol. 5, ,(2016) , 10.7554/ELIFE.16799