作者: R. G. Allen , R. S. Sohal
DOI: 10.1007/978-3-642-70853-4_13
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摘要: Glutathione is a tripeptide consisting of glutamic acid, cysteine and glycine moieties, found in all aerobes (Kosower Kosower 1976). may exist the reduced form (GSH) or as an oxidized dimer (GSSG). More than 90% glutathione contained cells GSH; form, GSSG, rapidly to GSH by reductase extruded from (Meister Anderson 1983). The cellular concentration usually high, exceeding one millimolar many tissues plays important role multiple physiological processes, due mainly its ability donate reducing equivalents; indeed, most equivalents are (Chance et al. 1979). Although principle detoxify potentially deleterious substances, including oxygen free radicals, it strongly modulates redox state cells, which function ratio oxidizing