Nosocomial bacteremia in neonates related to poor standards of care.

摘要: BACKGROUND: In developing countries, intravenous liquids are mixed and administered by nurses, sometimes under suboptimal infection control conditions. We hypothesized that outbreaks of infusate-associated neonatal bacteremias common, we evaluated whether they can be detected vigilant microbiologic surveillance infusates. METHODS: studied infusates to neonates in a Mexican hospital where mixtures were prepared wards. The study was performed 3 stages: stage 1, initial culturing in-use basal conditions; 2, prospective during cluster clinical sepsis; 3, final once the outbreak controlled. RESULTS: 68 sterile, 1 contaminated with Staphylococcus aureus (1.45%), from 23 patients. 182 39 patients, 51 (28%) Gram-negative rods. On first day 11 15 same strain Klebsiella pneumoniae, which continued appear for 26 days. Another 4 strains rods also isolated 2. association between infusate death significant (odds ratio, 9.4; 95% confidence interval, 2-44.3; P < 0.001). Mixtures made nurses more likely than commercial preparations 3.1; 1.1-8.5; = 0.037). there 42 sterile 22 patients. CONCLUSIONS: Our suggests poor standards care common hospitals countries result sepsis newborn