Pathogenesis of murine cytomegalovirus infection.

作者: Astrid Krmpotic , Ivan Bubic , Bojan Polic , Pero Lucin , Stipan Jonjic

DOI: 10.1016/J.MICINF.2003.09.007

关键词:

摘要: Infection of mice with murine cytomegalovirus (MCMV) is an established model for studying human (HCMV) infection. Similarly to HCMV infection, pathological changes and disease manifestations during MCMV infection are mainly dependent on the immune status mouse host. This review focuses pathogenesis in immunocompetent immunodeficient and/or immature discusses principles immunosurveillance mechanisms by which this virus evades control.

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