Cytotoxicity evaluation of ceramic particles of different sizes and shapes
作者： Akiko Yamamoto , Rieko Honma , Masae Sumita , Takao Hanawa
DOI: 10.1002/JBM.A.20020
关键词:
摘要: When artificial hip or knee joints are implanted in the human body, they release metallic, ceramic, and polymeric debris into surrounding tissues. The toxicity of released particles is two types: chemical, caused by soluble ions monomers, mechanical, a result mechanical stimulation produced insoluble particles. In this study, cytotoxicity TiO2, Al2O3, ZrO2, Si3N4, SiC for murine fibroblasts macrophages were examined to evaluate just their because these not expected metal ions. Different sizes shapes TiO2 used effect size shape on particle cytotoxicity. results suggest that ceramic does depend chemical species. Cytotoxicity levels lower than those corresponding ions, indicating monomers. differences did affect dendritic had higher level spindle spheric
sci-hub.se 参考文章(21)
John Christian Bailar, Harry Julius Emeléus, Sir Ronald Nyholm, A. F. Trotman-Dickenson, Comprehensive inorganic chemistry Pergamon Press , Compendium (Exclusive distributors in the Western Hemisphere). ,(1973)
G.L. Fisher, K.L. McNeill, J.T. Smith, In vitro effects of fibrous and nonfibrous silicon nitride on bovine pulmonary macrophages. Environmental Research. ,vol. 50, pp. 279- 288 ,(1989) , 10.1016/S0013-9351(89)80009-X
J. D. Birchall, D. R. Stanley, M. J. Mockford, G. H. Pigott, P. J. Pinto, Toxicity of silicon carbide whiskers Journal of Materials Science Letters. ,vol. 7, pp. 350- 352 ,(1988) , 10.1007/BF01730738
Akiko Yamamoto, Rieko Honma, Ayako Tanaka, Masae Sumita, Generic tendency of metal salt cytotoxicity for six cell lines Journal of Biomedical Materials Research. ,vol. 47, pp. 396- 403 ,(1999) , 10.1002/(SICI)1097-4636(19991205)47:3<396::AID-JBM15>3.0.CO;2-R
Isabelle Catelas, Alain Petit, David J. Zukor, Richard Marchand, L’Hocine Yahia, Olga L. Huk, Induction of macrophage apoptosis by ceramic and polyethylene particles in vitro. Biomaterials. ,vol. 20, pp. 625- 630 ,(1999) , 10.1016/S0142-9612(98)00214-2
Thomas P. Schmalzried, Pat Campbell, Alexandra K. Schmitt, Ian C. Brown, Harlan C. Amstutz, Shapes and dimensional characteristics of polyethylene wear particles generated in vivo by total knee replacements compared to total hip replacements Journal of Biomedical Materials Research. ,vol. 38, pp. 203- 210 ,(1997) , 10.1002/(SICI)1097-4636(199723)38:3<203::AID-JBM4>3.0.CO;2-T
Arun S. Shanbhag, Joshua J. Jacobs, Jonathan Black, Jorge O. Galante, Tibor T. Glant, Macrophage/particle interactions: Effect of size, composition and surface area Journal of Biomedical Materials Research. ,vol. 28, pp. 81- 90 ,(1994) , 10.1002/JBM.820280111
M.E. Martı́nez, S. Medina, M.T. del Campo, J.A. Garcı́a, Ana Rodrigo, L. Munuera, Effect of polyethylene particles on human osteoblastic cell growth Biomaterials. ,vol. 19, pp. 183- 187 ,(1998) , 10.1016/S0142-9612(97)00250-0
John C. Wataha, Carl T. Hanks, Zhilin Sun, Effect of cell line on in vitro metal ion cytotoxicity Dental Materials. ,vol. 10, pp. 156- 161 ,(1994) , 10.1016/0109-5641(94)90025-6
Jui-Sheng Sun, Hwa-Chang Liu, Walter Hong-Shong Chang, Jimmy Li, Feng-Huei Lin, Han-Cheng Tai, Influence of hydroxyapatite particle size on bone cell activities: An in vitro study Journal of Biomedical Materials Research. ,vol. 39, pp. 390- 397 ,(1998) , 10.1002/(SICI)1097-4636(19980305)39:3<390::AID-JBM7>3.0.CO;2-E