Noninvasive monitoring of cerebral oxygenation in preterm infants: preliminary observations.

摘要: A noninvasive optical method for bedside monitoring of cerebral oxygenation in small preterm infants was evaluated. Through differential absorbance near infrared light, changes the oxidation-reduction level cytochrome aa3, state hemoglobin and tissue blood volume were assessed transilluminated anterior field. Overall, oxygenated correlated significantly with transcutaneous oxygen, r = .44 p less than .0001; however, correlation best absence cardiorespiratory disease. Hypoxia or without bradycardia led to deoxygenation a shift aa3 more reduced state. When hypoxic episodes came series prolonged, reduction occurred simultaneous but its recovery base-line values sometimes lagged behind return oxygenation. In one infant large patent ductus arteriosus, even brief mild caused precipitous before any greater deoxygenation. This response disappeared after ductal ligation. general, antecedent oxygenation, severity duration deoxygenation, presence circulatory abnormalities all influenced hypoxia. Continuous can be performed on sick at bedside.