Physical vapor deposition of peptide nanostructures

作者: Becky Bank-Srour , Peter Becker , Leonid Krasovitsky , Alexander Gladkikh , Yuri Rosenberg

DOI: 10.1038/PJ.2013.19

关键词:

摘要: Biological units such as proteins and peptides have the intrinsic ability to self-assemble into natural biological nanostructures DNA strands, amyloid fibers. These assemblies become an inspiration for development of new supramolecular nanostructural materials self-assembled from chemically synthesized proteins. Bioinspired are in center interest research development, they considered a generation functional soft materials, which can be used variety applications. Peptide nanostructure deposition technology is key problem emerging field bottom-up nanotechnology these bioinspired nanomaterials. It has been mainly performed by solution or vapor transport method. In this study, we describe technique physical (PVD) biomolecules compatible with microelectronic allowing fabrication dense homogeneous peptide materials. We present deep insight self-assembly mechanism deposited our developed PVD technique, study their elementary growth stages investigation fine morphological packing structure, molecular composition, chemical properties. enabled us develop controllable fabricating nanostructures. A detailed applied diphenylalanine (FF) described, following nanostructures.Control properties The process FF consists stages: first linear-FF (L-FF) molecules adhere substrate forming amorphous layer, grows nanoclusters. Second, either PNT L-FF nano fiber cyclo-FF formed, depending on environment.

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