Psychosocial factors and type 1 diabetes

摘要: Introduction: Psychosocial factors have been associated with outcomes in the general population and type 2 diabetes, yet rarely those 1 diabetes. We previously demonstrated that type A behavior is lower mortality risk, while higher depression symptoms are associated an increased risk. In addition, stressful life events previously demonstrated to lead and poor glycemic control 1 diabetes. Methods: aimed further understand relationship through assessment of potential mediators, moderators, confounders, well as by examining the different Bortner Rating Scale scoring methods using Cox proportional hazards modeling. We also investigated which psychosocial factors, including trait-anger, interacted depressive symptoms predict mortality, again utilizing Lastly, we investigated whether scores were high symptoms or a change logistic linear regression. Results: found that was no longer significantly predictive after the additions age, inflammatory markers/stress reactants, waist-to-hip ratio, the item “fast eater, walker, etc.” best predictor but also lost significance multivariable Next, we depressive symptoms,independent anxiety stress, risk only low anger scores. high depressive symptomatology, not control. Discussion: Along established, physiological diabetes care play important role outcome development. These very understudied, thus this work has large public health impact. line with earlier theories locus control, may impact on through variety pathways following diagnosis. Future research should focus exploring these individual predictors examining them clinical trial setting potentially improve outcomes.