摘要: The etiology of psoriasis remains obscure. primary site involvement tissues, namely, epidermis, dermis or vasculature is equally doubtful. This study was undertaken to elucidate, if possible, in which structure the first change can be localized. present thoughts on this subject are well stated by Shelley and Arthur (1). Kuta Neumann, (2) investigated changes dehydrogenase activity epidermal cells after trauma. They report that there an increase enzyme earlier than any other observed change. earliest biopsy reported sixth day it showed histologically only nonspecific acanthosis. Szodoray (3), reports specimens taken at various time intervals trauma skin. His findings tend place capillaries.