Neuropsychology of deep brain stimulation in neurology and psychiatry

摘要: Deep brain stimulation (DBS) experienced resurgence in the 1990s when limitations pharmacotherapy and ablative surgery for movement disorders (including neuropsychological deficits) were appreciated. Subthalamic DBS Parkinson's disease has received most empirical attention may entail cognitive psychiatric adverse events approximately 10% of patients. This article reviews alterations after thalamic, pallidal, subthalamic (including, disease, essential tremor, dystonia) possible etiology mechanisms underlying neurobehavioral changes. Initial studies outcomes emerging indications such as epilepsy, obsessive compulsive disorder, depression, Tourette's syndrome, persistent vegetative or minimally conscious state are also reviewed. currently accepted appears safe from a standpoint that procedure is associated with typically transient, mild, circumscribed (most commonly verbal fluency), improved mood quality life. A minority patients experience more widespread, persistent, serious sequelae, although research to date failed identify reliable risk factors events.