作者: Luis M. Carcoba , Oscar V. Torres , Joseph A. Pipkin , Tiahna Ontiveros , Laura E. O’Dell
DOI: 10.1007/S40429-016-0091-1
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摘要: It is presently unclear why certain populations are more vulnerable to tobacco use and less responsive smoking cessation interventions. This review considers the contribution of nicotine reward withdrawal in that appear be susceptible use. Our focus on have been modeled rodents including, adolescents, females, persons with metabolic disorders, such as diabetes. A common feature across these rodent models heightened reward, suggesting may experience strong rewarding effects promote One distinguishing factor among at-risk regard magnitude withdrawal, which lower during adolescence. These groups also differ expression physical signs versus affective states produced by distinct facets differentially contribute populations. Thus, we need apply different diagnostic criteria and/or specialized treatments target unique factors