Pinpointing mechanochemical bond rupture by embedding the mechanophore into a macrocycle.
作者： Doreen Schütze , Katharina Holz , Julian Müller , Martin K. Beyer , Ulrich Lüning
关键词:
摘要: Mechanophores contain a mechanically labile bond that can be broken by an external mechanical force. Quantitative measurement and control of the applied force is possible through atomic microscopy (AFM). A macrocycle was synthesized contains both mechanophore aliphatic chain acts as "safety line" upon breaking. This ring-opening unit linked to poly(ethylene glycol) spacers, which allow investigation single molecule spectroscopy. The length increase rupture measured compared with quantum chemical calculations.
geomar.de
sci-hub.se 参考文章(47)
Johnathan N Brantley, Kelly M Wiggins, Christopher W Bielawski, Polymer mechanochemistry: the design and study of mechanophores Polymer International. ,vol. 62, pp. 2- 12 ,(2013) , 10.1002/PI.4350
Yuan Lin, Qian Wang, Öffnen des 1,2,3‐Triazolrings mithilfe mechanischer Kräfte Angewandte Chemie. ,vol. 124, pp. 2046- 2047 ,(2012) , 10.1002/ANGE.201108044
Ute F. Röhrig, Irmgard Frank, First-principles molecular dynamics study of a polymer under tensile stress The Journal of Chemical Physics. ,vol. 115, pp. 8670- 8674 ,(2001) , 10.1063/1.1411995
Michael F. Pill, Alfred Kersch, Hauke Clausen-Schaumann, Martin K. Beyer, Sebastian W. Schmidt, Mechanically induced silyl ester cleavage under acidic conditions investigated by AFM-based single-molecule force spectroscopy in the force-ramp mode Faraday Discussions. ,vol. 170, pp. 357- 367 ,(2014) , 10.1039/C3FD00119A
E. Florin, V. Moy, H. Gaub, Adhesion forces between individual ligand-receptor pairs. Science. ,vol. 264, pp. 415- 417 ,(1994) , 10.1126/SCIENCE.8153628
Yuan Lin, Qian Wang, Unlocking the 1,2,3‐Triazole Ring Using Mechanical Force Angewandte Chemie. ,vol. 51, pp. 2006- 2007 ,(2012) , 10.1002/ANIE.201108044
Peter Schwaderer, Enno Funk, Frank Achenbach, Johann Weis, Christoph Bräuchle, Jens Michaelis, Single-molecule measurement of the strength of a siloxane bond. Langmuir. ,vol. 24, pp. 1343- 1349 ,(2008) , 10.1021/LA702352X
Sebastian W. Schmidt, Martin K. Beyer, Hauke Clausen-Schaumann, Dynamic Strength of the Silicon-Carbon Bond Observed over Three Decades of Force-Loading Rates Journal of the American Chemical Society. ,vol. 130, pp. 3664- 3668 ,(2008) , 10.1021/JA710642A
Jian Liang, Julio M. Fernández, Kinetic measurements on single-molecule disulfide bond cleavage. Journal of the American Chemical Society. ,vol. 133, pp. 3528- 3534 ,(2011) , 10.1021/JA109684Q
Matthias Rief, Filipp Oesterhelt, Berthold Heymann, Hermann E Gaub, Single Molecule Force Spectroscopy on Polysaccharides by Atomic Force Microscopy Science. ,vol. 275, pp. 1295- 1297 ,(1997) , 10.1126/SCIENCE.275.5304.1295