Synthesis of Platinum(II) Complexes with Some 1-Methylnitropyrazoles and In Vitro Research on Their Cytotoxic Activity.
作者： Henryk Mastalarz , Agnieszka Mastalarz , Joanna Wietrzyk , Magdalena Milczarek , Andrzej Kochel
DOI: 10.3390/PH13120433
关键词:
摘要: A series of eight novel platinum(II) complexes were synthesized by the reaction of the … K 2 PtCl 4 and characterized by elemental analysis, ESI MS spectrometry, 1 H NMR, 195 Pt NMR, …
mdpi.com
sci-hub.st 参考文章(54)
Anna Zięba-Mizgała, Aniela Puszko, Andrzej Regiec, Janina Kuduk-Jaworska, Electrophilic properties of nitroheterocyclic compounds. Potential hypoxic cells radiosensitizers. Bioelectrochemistry. ,vol. 65, pp. 113- 119 ,(2005) , 10.1016/J.BIOELECHEM.2004.10.003
Brown Jm, The hypoxic cell: a target for selective cancer therapy--eighteenth Bruce F. Cain Memorial Award lecture. Cancer Research. ,vol. 59, pp. 5863- 5870 ,(1999)
N. P. Farrell, Multi-platinum anti-cancer agents. Substitution-inert compounds for tumor selectivity and new targets. Chemical Society Reviews. ,vol. 44, pp. 8773- 8785 ,(2015) , 10.1039/C5CS00201J
Phyllis M. Goddard, Melanie Valenti, Mervyn Jones, Barry A. Murrer, George Abel, Mark J. McKeage, Kenneth R. Harrap, Lloyd R. Kelland, Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): an orally active platinum drug. Cancer Research. ,vol. 53, pp. 2581- 2586 ,(1993)
F I Raynaud, P M Goddard, M Valenti, F E Boxall, B A Murrer, L R Kelland, M Abrams, M Jones, cis-Amminedichloro(2-methylpyridine) platinum(II) (AMD473), a novel sterically hindered platinum complex: in vivo activity, toxicology, and pharmacokinetics in mice. Clinical Cancer Research. ,vol. 3, pp. 2063- 2074 ,(1997)
Mauro Coluccia, Giovanni Natile, Trans-Platinum Complexes in Cancer Therapy Anti-cancer Agents in Medicinal Chemistry. ,vol. 7, pp. 111- 123 ,(2007) , 10.2174/187152007779314080
George M. Sheldrick, Crystal structure refinement with SHELXL Acta Crystallographica Section C-crystal Structure Communications. ,vol. 71, pp. 3- 8 ,(2015) , 10.1107/S2053229614024218
Lana Filipovic, Sandra Arandelovic, Nevenka Gligorijevic, Ana Krivokuca, Radmila Jankovic, Tatjana Srdic-Rajic, Gordana Rakic, Zivoslav Tesic, Sinisa Radulovic, Biological evaluation of transdichloridoplatinum( II) complexes with 3- and 4-acetylpyridine in comparison to cisplatin Radiology and Oncology. ,vol. 47, pp. 346- 357 ,(2013) , 10.2478/RAON-2013-0050
Andrzej Regiec, Piotr Wojciechowski, Henryk Mastalarz, Experimental and theoretical spectroscopic and electronic properties enriched with NBO analysis for 1-methyl-3-nitropyrazole and 1-methyl-5-nitropyrazole Journal of Molecular Structure. ,vol. 1075, pp. 234- 245 ,(2014) , 10.1016/J.MOLSTRUC.2014.06.088
V. Papesch, R. M. Dodson, Isomeric Pyrazolo[4,3-d]pyrimidinediones Journal of Organic Chemistry. ,vol. 30, pp. 199- 203 ,(1965) , 10.1021/JO01012A046