Antigen-Specific Suppression of Antibody Responses by Class II MHC-Restricted CTL
作者： Nobukata Shinohara
DOI: 10.1007/978-1-4684-6814-4_37
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摘要: Mature T cells are known to be capable of suppressing immune responses in an antigen-specific manner. However the mechanism suppression is not known. Despite many reports indicating existence “suppressor cells” secreting suppressor factors with affinity for native antigens, no evidence on a molecular level available. Recent studies class II-restricted cytotoxic lymphocytes (CTL) raised possibility that such CTL might explain antibody by cells. Thus, play role regulation as well elimination pathological
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Masaharu Kojima, Masaru Taniguchi, Nobukata Shinohara, Mouse alloantibodies capable of blocking cytotoxic T cell function. IV. Comparative analysis of the blocking effects of anti-Lyt-2 and anti-H-2 antibodies on allogeneic and PHA-mediated killing. Microbiology and Immunology. ,vol. 27, pp. 1093- 1105 ,(1983) , 10.1111/J.1348-0421.1983.TB02930.X
M Kojima, N Shinohara, Mouse alloantibodies capable of blocking cytotoxic T cell function. V. The majority of I region-specific CTL are Lyt-2+ but are relatively resistant to anti-Lyt-2 blocking. Journal of Immunology. ,vol. 132, pp. 578- 583 ,(1984)
A K Abbas, D Liano, Antigen presentation by hapten-specific B lymphocytes. V. Requirements for activation of antigen-presenting B cells. Journal of Immunology. ,vol. 139, pp. 2562- 2566 ,(1987)
H Golding, A Singer, Specificity, phenotype, and precursor frequency of primary cytolytic T lymphocytes specific for class II major histocompatibility antigens. Journal of Immunology. ,vol. 135, pp. 1610- 1615 ,(1985)
V S Hinshaw, C E Hioe, Induction and activity of class II-restricted, Lyt-2+ cytolytic T lymphocytes specific for the influenza H5 hemagglutinin. Journal of Immunology. ,vol. 142, pp. 2482- 2488 ,(1989)
V L Braciale, L A Morrison, M M Maimone, T J Braciale, Features of target cell lysis by class I and class II MHC restricted cytolytic T lymphocytes Journal of Immunology. ,vol. 137, pp. 3639- 3643 ,(1986)
Nobukata Shinohara, Class II antigen-specific murine cytolytic T lymphocytes (CTL) Cellular Immunology. ,vol. 107, pp. 395- 407 ,(1987) , 10.1016/0008-8749(87)90247-4
V L Braciale, L A Morrison, T J Braciale, Expression of H-2I region-restricted cytolytic activity by an Lyt-2+ influenza virus-specific T lymphocyte clone. Journal of Immunology. ,vol. 135, pp. 3691- 3696 ,(1985)
J A Bluestone, R Johnson-Leva, N Shinohara, D H Sachs, N Hozumi, M Watanabe, Class II antigen-specific murine cytolytic T lymphocytes (CTL). II. Genuine class II specificity of Lyt-2+ CTL clones. Journal of Immunology. ,vol. 140, pp. 30- 36 ,(1988)
M B Powell, J P Tite, N H Ruddle, Protein-antigen specific Ia-restricted cytolytic T cells: analysis of frequency, target cell susceptibility, and mechanism of cytolysis. Journal of Immunology. ,vol. 135, pp. 25- 33 ,(1985)