Mitochondria and cancer relationship

摘要: Cancer cells are characterized by an altered metabolism as compared with normal cells, on the point of view cancer a metabolic disease, detected firstly Otto Warburg in 1924, known effect. Aerobic glycolysis is central event involved carcinogenesis, and mitochondria main component this process. The most crucial role related to recent evidences involvement cell immortality induction metastasis from their origin site, spreading transformed for elsewhere body, originating other cancers. Summarizing, mitochondrial dysfunction has many diseases including cancer; however, mechanisms not fully known, order detect effective therapeutic targets. There several interesting researches progress, throw light understanding these microscopy, together tools, gives doubtless great contribution. Some references methodologies visualization presented, based distinct technologies, complementing review.