Effects of a novel calcium aluminate cement on the early events of the progression of osteogenic cell cultures

摘要: The present study evaluated the progression of osteogenic cell cultures exposed to a novel calcium aluminate cement (CAC+) in comparison with gold standard mineral trioxide aggregate (MTA). Cells were enzimatically isolated from newborn rat calvarial bone, plated on glass coverslips containing either CAC+ or control MTA samples center, and grown under conditions. Over 10-day culture period, roundening sample edges was clearly noticed only for group. Although both cements supported adhesion, spreading, proliferation, CAC+-exposed showed significantly higher values terms total number at days 3 7, protein content alkaline phosphatase activity day 10. vitro results indicate that exposure supports differentiation cells compared ones MTA. Further experimental studies should consider as potential alternative when repair mineralized tissues is one desired outcomes endodontic therapy.