Inhibitor of Nicotinamide Phosphoribosyltransferase Sensitizes Glioblastoma Cells to Temozolomide via Activating ROS/JNK Signaling Pathway.

作者: Jun Feng , Peng-Fei Yan , Hong-yang Zhao , Fang-Cheng Zhang , Wo-Hua Zhao

DOI: 10.1155/2016/1450843

关键词:

摘要: Overcoming temozolomide (TMZ) resistance is a great challenge in glioblastoma (GBM) treatment. Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting enzyme in the …

参考文章(67)
Ardeshir Hakam, Domenico Coppola, Marilyn M Bui, Rodney E Shackelford, Over-expression of nicotinamide phosphoribosyltransferase in ovarian cancers. International Journal of Clinical and Experimental Pathology. ,vol. 3, pp. 522- 527 ,(2010)
Marta Pulido-Salgado, Jose M. Vidal-Taboada, Josep Saura, C/EBPβ and C/EBPδ transcription factors: Basic biology and roles in the CNS Progress in Neurobiology. ,vol. 132, pp. 1- 33 ,(2015) , 10.1016/J.PNEUROBIO.2015.06.003
Antonia Cagnetta, Irene Caffa, Chirag Acharya, Debora Soncini, Prakrati Acharya, Sophia Adamia, Ivana Pierri, Micaela Bergamaschi, Anna Garuti, Giulio Fraternali, Luca Mastracci, Alessandro Provenzani, Chiara Zucal, Gianluca Damonte, Annalisa Salis, Fabrizio Montecucco, Franco Patrone, Alberto Ballestrero, Santina Bruzzone, Marco Gobbi, Alessio Nencioni, Michele Cea, APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells Clinical Cancer Research. ,vol. 21, pp. 3934- 3945 ,(2015) , 10.1158/1078-0432.CCR-14-3023
Yan Zhao, Yun-Feng Guan, Xiao-Ming Zhou, Guo-Qiang Li, Zhi-Yong Li, Can-Can Zhou, Pei Wang, Chao-Yu Miao, Regenerative Neurogenesis After Ischemic Stroke Promoted by Nicotinamide Phosphoribosyltransferase–Nicotinamide Adenine Dinucleotide Cascade Stroke. ,vol. 46, pp. 1966- 1974 ,(2015) , 10.1161/STROKEAHA.115.009216
Alexei Verkhratsky, Luca Steardo, Vladimir Parpura, Vedrana Montana, Translational potential of astrocytes in brain disorders Progress in Neurobiology. ,vol. 144, pp. 188- 205 ,(2016) , 10.1016/J.PNEUROBIO.2015.09.003
Mary Frances McAleer, Paul D Brown, Therapeutic management of gliosarcoma in the temozolomide era CNS oncology. ,vol. 4, pp. 171- 178 ,(2015) , 10.2217/CNS.14.61
Myeong Jin Yoon, Mitsukuni Yoshida, Sean Johnson, Akiko Takikawa, Isao Usui, Kazuyuki Tobe, Takashi Nakagawa, Jun Yoshino, Shin-ichiro Imai, SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice Cell Metabolism. ,vol. 21, pp. 706- 717 ,(2015) , 10.1016/J.CMET.2015.04.002
Simon E. Hufton, Peter T. Moerkerk, Ricardo Brandwijk, Adriaan P. de Bruïne, Jan-Willem Arends, Hennie R. Hoogenboom, A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization FEBS Letters. ,vol. 463, pp. 77- 82 ,(1999) , 10.1016/S0014-5793(99)01578-1
Deepak Sampath, Tanja S. Zabka, Dinah L. Misner, Thomas O’Brien, Peter S. Dragovich, Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer Pharmacology & Therapeutics. ,vol. 151, pp. 16- 31 ,(2015) , 10.1016/J.PHARMTHERA.2015.02.004
L. R. Stein, D. F. Wozniak, J. T. Dearborn, S. Kubota, R. S. Apte, Y. Izumi, C. F. Zorumski, S.-i. Imai, Expression of Nampt in Hippocampal and Cortical Excitatory Neurons Is Critical for Cognitive Function The Journal of Neuroscience. ,vol. 34, pp. 5800- 5815 ,(2014) , 10.1523/JNEUROSCI.4730-13.2014