Hdac inhibitor polymorphic forms and methods of use

Harry G Brittain, None, Polymorphism in Pharmaceutical Solids ,(1999)

Joel Bernstein, Polymorphism in Molecular Crystals ,(2020)

Mei-Chuan Chen, Chun-Han Chen, Hsiao-Ching Chuang, Samuel K. Kulp, Che-Ming Teng, Ching-Shih Chen, Novel mechanism by which histone deacetylase inhibitors facilitate topoisomerase IIα degradation in hepatocellular carcinoma cells Hepatology. ,vol. 53, pp. 148- 159 ,(2011) , 10.1002/HEP.23964

Yen-Shen Lu, Yoko Kashida, Samuel K. Kulp, Yu-Chieh Wang, Dasheng Wang, Jui-Hsiang Hung, Monica Tang, Zhong-Zhe Lin, Te-Jung Chen, Ann-Lii Cheng, Ching-Shih Chen, Efficacy of a novel histone deacetylase inhibitor in murine models of hepatocellular carcinoma Hepatology. ,vol. 46, pp. 1119- 1130 ,(2007) , 10.1002/HEP.21804

A Mims, A R Walker, X Huang, J Sun, H Wang, R Santhanam, A M Dorrance, C Walker, P Hoellerbauer, S S Tarighat, K K Chan, R B Klisovic, D Perrotti, M A Caligiuri, J C Byrd, C-S Chen, L James Lee, S Jacob, K Mrózek, C D Bloomfield, W Blum, R Garzon, S Schwind, G Marcucci, Increased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: a novel epigenetic-targeting approach in acute myeloid leukemia. Leukemia. ,vol. 27, pp. 871- 878 ,(2013) , 10.1038/LEU.2012.342

Shuhong Zhang, Attaya Suvannasankha, Colin D. Crean, Valerie L. White, Ching-Shih Chen, Sherif S. Farag, The novel histone deacetylase inhibitor, AR-42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells. International Journal of Cancer. ,vol. 129, pp. 204- 213 ,(2011) , 10.1002/IJC.25660

Christine B. Yoo, Peter A. Jones, Epigenetic therapy of cancer: past, present and future Nature Reviews Drug Discovery. ,vol. 5, pp. 37- 50 ,(2006) , 10.1038/NRD1930

Yen-Shen Lu, Chia-Hung Chou, Kai-Yuan Tzen, Ming Gao, Ann-Lii Cheng, Samuel K. Kulp, Jason Chia-Hsien Cheng, Radiosensitizing Effect of a Phenylbutyrate-Derived Histone Deacetylase Inhibitor in Hepatocellular Carcinoma International Journal of Radiation Oncology*Biology*Physics. ,vol. 83, pp. e181- e189 ,(2012) , 10.1016/J.IJROBP.2011.12.022

Qiang Lu, Ya-Ting Yang, Chang-Shi Chen, Melanie Davis, John C. Byrd, Mark R. Etherton, Asad Umar, Ching-Shih Chen, Zn2+ -chelating motif-tethered short -chain fatty acids as a novel class of histone deacetylase inhibitors Journal of Medicinal Chemistry. ,vol. 47, pp. 467- 474 ,(2004) , 10.1021/JM0303655

Bevin Zimmerman, Aaron Sargeant, Kristina Landes, Soledad A. Fernandez, Ching-Shih Chen, Michael D. Lairmore, Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human T-lymphotropic virus type 1 adult T cell lymphoma Leukemia Research. ,vol. 35, pp. 1491- 1497 ,(2011) , 10.1016/J.LEUKRES.2011.07.015