Temperature- and pH-responsive star amphiphilic block copolymer prepared by a combining strategy of ring-opening polymerization and reversible addition–fragmentation transfer polymerization
作者： Jianhua Zhou , Li Wang , Jianzhong Ma , Jianjun Wang , Haojie Yu
DOI: 10.1016/J.EURPOLYMJ.2010.03.004
关键词:
摘要: Abstract The star-shaped poly(e-caprolactone)-b-poly(2-(dimethylamino)ethyl methacrylate) (HPs-Star-PCL-b-PDMAEMA) was synthesized by ring-opening polymerization and reversible addition–fragmentation chain transfer (RAFT) polymerization. Star-shaped polycaprolactones (HPs-Star-PCL) were the bulk of e-caprolactone (CL) with a hyperbranched polyester initiator tin 2-ethylhexanoate as catalyst. number-average molecular weight these polymers linearly increased increase molar ratio CL to initiator. HPs-Star-PCL converted into HPs-star-PCL-RAFT an esterification 4-cyanopentanoic acid dithiobenzoate. Star amphiphilic block copolymer HPs-Star-PCL-b-PDMAEMA obtained via RAFT 2-(dimethylamino)ethyl methacrylate (DMAEMA). distribution narrow. Furthermore, micellar properties in water studied at various temperatures pH values means dynamic light scattering (DLS). results indicated that star copolymers had pH- temperature-responsive properties. release behaviors model drug aspirin from polymer rate could be effectively controlled value temperature.
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